Welcome to the Glass Lab

N. Louise Glass

We're based in the Department of Plant & Microbial Biology at the University of California, Berkeley. 
Our lab is interested in cell specialization, communication and nonself recognition, all crucial mechanisms in microbial organisms such as filamentous fungi.

Some of our research interests are focused on understanding the signaling mechanisms that mediate cell fusion and the nonself recognition mechanisms that occur before and after fusion. 

The experimental tractability and availability of a large number of mutants in the filamentous fungus Neurospora crassa makes it a superb system to delineate both fungal-specific and general mechanisms of cell communication and nonself recognition.

We use a combination of molecular biology, genetics, cell biology, genomics and bioinformatics to investigate these subjects.

 Recently we have begun to study how plant cell wall degradation is orchestrated by fungi, and how fungal enzymes are secreted. Our long term goal for this project is to significantly improve the efficiency of plant biomass degradation by fungi. Neurospora crassa is a model cellulolytic fungus, thus we are also using this species for these studies.

 

Glass Lab present at ECFG14

ECFG14
Darae and Gabe represented the Glass Lab at the 14th European Conference on Fungal Genetics in Haifa, Israel. Gabe received an award for his poster on germling communication and Darae presented her work on new genes involved in secretion in Neurospora.

Glass Lab discovers a fungal NLR surveillance system

NLR surveillance of essential SEC-9 SNARE proteins induces programmed cell death upon allorecognition in filamentous fungi
A new study by Jens Heller et al demonstrates that fungal NLRs function similar to NLRs in plants and animals, indicating that these fundamental players of innate immunity evolved independently in all three kingdoms.

Glass Lab at the Fungal Cell Wall 2017 Conference

Fungal Cell Wall 2017 Conference
Pedro and Darae were the representatives of the Glass Lab at the Fungal Cell Wall Conference 2017, in Ensenada, Mexico. Both had a poster and Pedro gave a talk for an auditorium full of fungal cell wall connoisseurs.

Louise Glass to receive the MSA Fellow Award

Mycological Society of America
Louise Glass is being named a Fellow of the Mycological Society of America, recognizing her research advances in mycology and her service to the MSA.

Congratulation Jens and Lori!

Fungal Genetics Conference
Congratulations Jens Heller and Lori Huberman! GSA poster prize at the FG Conference.

Jens Heller wins the Postdoc Leadership Award

Jens Heller
Glass Lab postdoc Jens Heller wins the Postdoc Leadership Award at the National Postdoc Appreciation Day!

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