Welcome to the Glass Lab

N. Louise Glass

We're based in the Department of Plant & Microbial Biology at the University of California, Berkeley. 
Our lab is interested in cell specialization, communication and nonself recognition, all crucial mechanisms in microbial organisms such as filamentous fungi.

Some of our research interests are focused on understanding the signaling mechanisms that mediate cell fusion and the nonself recognition mechanisms that occur before and after fusion. 

The experimental tractability and availability of a large number of mutants in the filamentous fungus Neurospora crassa makes it a superb system to delineate both fungal-specific and general mechanisms of cell communication and nonself recognition.

We use a combination of molecular biology, genetics, cell biology, genomics and bioinformatics to investigate these subjects.

 Recently we have begun to study how plant cell wall degradation is orchestrated by fungi, and how fungal enzymes are secreted. Our long term goal for this project is to significantly improve the efficiency of plant biomass degradation by fungi. Neurospora crassa is a model cellulolytic fungus, thus we are also using this species for these studies.


Neurospora Conference 2018

Neurospora 2018
The Glass lab was represented at the 2018 Neurospora Conference, in Asilomar.

The Glass Lab welcomes our fall/winter visitors

Linfang, Natalia, Sara
Natalia, Sara and Linfang will be sharing their research and experience with us during the next couple of months.

Glass Lab at the International Mycological Congress

International Mycological Congress
Monika and Pedro represented the Glass Lab at the IMC11 - International Mycological Congress 2018, in San Juan, Puerto Rico.

Glass Lab at the GRC - Cellular and Molecular Fungal Biology

Gordon Research Conference
Asen, Lori and Louise represented the Glass Lab at the 2018 Gordon Research Conference - Cellular and Molecular Fungal Biology

Glass Lab present at ECFG14

Darae and Gabe represented the Glass Lab at the 14th European Conference on Fungal Genetics in Haifa, Israel. Gabe received an award for his poster on germling communication and Darae presented her work on new genes involved in secretion in Neurospora.

Glass Lab discovers a fungal NLR surveillance system

NLR surveillance of essential SEC-9 SNARE proteins induces programmed cell death upon allorecognition in filamentous fungi
A new study by Jens Heller et al demonstrates that fungal NLRs function similar to NLRs in plants and animals, indicating that these fundamental players of innate immunity evolved independently in all three kingdoms.


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